Welcome to the 

Biostructural Interactions Group!

We study the molecular mechanisms and motions of (membrane) proteins from microorganism to man

Lab News!

09/21 - Zoe joins us from California with a Fulbright Fellowship! Congratulations and welcome to Germany, we are very excited to have you over! 

09/21 - We are very happy to welcome Alina and Jean, who will do their PhDs with us! Great to have you on board!

08/21 - Congratulations, Dr Erika! During her PhD thesis Erika wrestled many secrets from the human ion channel TRPV4 and its protein partners. We will miss you a lot but wish you all the best for the next adventures in Frankfurt! 

08/21 - Emma submitted her BSc thesis! Congratulations!

07/21 - The first of many lab BBQs in Jena! Finally we got to try the famous Thüringer Bratwurst and just enjoy each other's company in person.  Also, followed by yet another a legendary game night hosted by Mai... 

07/21 - A happy welcome to Kira, our first Master student in Jena! Enjoy the science and good luck with everything!

06/21 - We welcome our new team assistant Katja! Great to have you on board! 

New Publications!

What a difference a single fluorine can make - new paper with Schirmeister lab ranging from inhibitor synthesis via functional protein assays, QM/MM calculations, parasite cell culture all the way to mouse models now accepted in J. Med. Chem.! Congratulations everyone!

New paper on the conformational dynamics of Dengue virus protease by smFRET with the Basché and Schirmeister labs in Mainz accepted in J Phys Chem B! This also brings former MSc student Luca's count to three papers from his thesis! Congratulations everyone!

Our review on TRP channel UNstructural biology has been accepted in J. Mol. Biol.! We analyze all 175 currently available TRP structures with regard to intrinsic disorder and discuss cool (pun fully intended) examples of how intrinsically disordered regions affect channel function, e.g. temperature sensing!

Two new papers on the T. brucei protease rhodesain! You can read about Patrick's work on rhodesain's complex maturation and covalent inhibition kinetics in J. Biol. Chem. and ACS Chem. Biol.! As always a fun collaboration with the Schirmeister (Mainz) and Neuweiler (Würzburg) labs!

Awards and Recognitions!

Charlotte received a best talk award at the 2021 Science Day in Mainz! Congratulations!

Annika is selected for the 5-week Marine Biological Laboratory "Biology of Parasitism" Course in Woods Hole, MA, USA! Super! 

We are very grateful to be supported by a grant from the Helaba together with our colleagues from the Goethe-University Frankfurt and the Covid-19 NMR initiative

Ute is elected onto the advisory board of the Joint Group Chemical Biology of the  DECHEMA, GDCh, DPhG and GBM 

Eric is selected to give a talk at MiCom 2021! Looking forward to hearing about your exciting research!

Benedikt's and Julia's (Neuweiler lab in Würzburg) work on spider silk wins the ChemBioChem poster prize at the DECHEMA Advances in Chemical Biology Meeting! Yay!

Eric was selected to give a talk at the  29th Annual Meeting of the German Society of Parasitology! We cannot wait to hear your talk! 

Benedikt wins poster award at the EMBL SAXS Meeting! Congratulations, Bene! 

How to find us:

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Hellmich Group 

Biostructural Interactions

Contact us:
Office: Katja Konscholky

Lab: Sabine Häfner, Hannah Niederlechner

Friedrich-Schiller-Universität Jena

Faculty of Chemistry and Earth Sciences
Institute of Organic and Macromolecular Chemistry
Cluster of Excellence "Balance of the Microverse"

Beutenberg Labs and Office:
Bioinstrumentezentrum (BIZ)
Winzerlaer Str. 2, 07745 Jena

IOMC Labs and NMR:
Humboldtstrasse 10, 07743 Jena