Welcome to the 

Biostructural Interactions Group!

We study the molecular mechanisms and motions of (membrane) proteins from microorganism to man

Lab News!

08/2023 - A new Dr in the house! Congratulations Kerstin on a fantastic job bringing TRP channels and flaviviruses together in a super multidisciplinary PhD!

07/2023 - We welcome Sreelakshmi and Leonie, our new PhD students to the team!

05/2023 - BIG news as our new 800 MHz NMR ascend spectrometer is delivered - it literally flew into the NMR platform!!! Exciting times ahead for biostructural interactions! Big thank you to the University, the Cluster of Excellence and EU-EFRE REACT for making this possible!

05/2023 A big thank you to the Cluster of Excellence Balance of the Microverse to throw the Allen Lab and us an amazing Lab Warming Party! It feels great to be part of this community!


New Publications!

Our paper on the structural dynamics & regulation of TRPV4 by its intrinsically disordered regions has been accepted in Nature Communications! Congratulations Bene, Christoph and all other co-authors!

New paper with the Basche and Schirmeister labs accepted on Zika virus protease dynamics accepted in Eur J Med Chem!  From our lab Victor was involved - congratulations to all authors! 

Two new pre-prints on microbial virulence factors, their structural dynamics and interaction with inhibitors now available on bioRxiv and chemRxiv!

Our new pre-print on the regulation of the TRPV4 ion channel by its intrinsically disordered N-terminus now on bioRxiv

Awards and Recognitions!

Ute is invited to join the selection committe for the Fulbright-Cottrell Award! 

Our lab is now part of three collaborative research centers funded by the DFG! CRC 1127 'ChemBioSys - Chemical Mediators in Complex Biosystems';  CRC 1278 'PolyTarget -  Polymer-based nanoparticle libraries for targeted anti-inflammatory strategies' and  CRC 1507 'Membrane-associated Protein Assemblies, Maschineries and Supercomplexes'! 

Eric is selected to join the  

TrypsSchool (Sao Paulo School of Advanced  Science on Pathogenic Trypanosomatids)! Congratulations! 

How to find us:

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Hellmich Group 

Biostructural Interactions
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Contact us:

Office: Katja Konscholky

Lab: Sabine Häfner, Hannah Niederlechner

Friedrich-Schiller-Universität Jena

Faculty of Chemistry and Earth Sciences
Institute of Organic and Macromolecular Chemistry
Cluster of Excellence "Balance of the Microverse"

Beutenberg Labs:
Bioinstrumentezentrum (BIZ)
Modul 2, Ebene 4
Winzerlaer Str. 2, 07745 Jena

IOMC Labs:
Humboldtstrasse 10, 07743 Jena